Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.
Identifieur interne : 000577 ( Main/Exploration ); précédent : 000576; suivant : 000578Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.
Auteurs : Grant W. Waterer [Australie, États-Unis] ; Jordi Rello [Espagne, France]Source :
- Infectious diseases and therapy [ 2193-8229 ] ; 2020.
Abstract
COVID-19 is a new infectious disease causing severe respiratory failure and death for which optimal treatment is currently unclear. Many therapies have been proven to be ineffective; however, promising findings related to corticosteroid therapy have been published. Analysis of published data including in this issue suggests that therapy with corticosteroids in the range of 6 mg of dexamethasone (or equivalent) per day likely has a positive effect in patients requiring mechanical ventilation but there remains considerable doubt in patients over the age of 70, in patients with diabetes and patients with milder disease. Clinicians must consider the individual potential risks and benefits of corticosteroid in patients with COVID-19 rather than routinely using them until more data is available.
DOI: 10.1007/s40121-020-00338-x
PubMed: 32936438
Affiliations:
- Australie, Espagne, France, États-Unis
- Catalogne, Communauté de Madrid, Illinois, Languedoc-Roussillon, Occitanie (région administrative)
- Barcelone, Madrid, Nîmes
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.</title>
<author><name sortKey="Waterer, Grant W" sort="Waterer, Grant W" uniqKey="Waterer G" first="Grant W" last="Waterer">Grant W. Waterer</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Western Australia, Perth, Australia. grant.waterer@uwa.edu.au.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Western Australia, Perth</wicri:regionArea>
<wicri:noRegion>Perth</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:affiliation>Northwestern University, Chicago, IL, USA. grant.waterer@uwa.edu.au.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Northwestern University, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rello, Jordi" sort="Rello, Jordi" uniqKey="Rello J" first="Jordi" last="Rello">Jordi Rello</name>
<affiliation wicri:level="3"><nlm:affiliation>Centro de Investigación Biomedica en Red (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Investigación Biomedica en Red (CIBERES), Instituto de Salud Carlos III, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Vall d'Hebron Institute of Research (VHIR), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Clinical Research, CHU Nîmes, Université Montpellier-Nîmes, Nîmes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Research, CHU Nîmes, Université Montpellier-Nîmes, Nîmes</wicri:regionArea>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Languedoc-Roussillon</region>
<settlement type="city">Nîmes</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32936438</idno>
<idno type="pmid">32936438</idno>
<idno type="doi">10.1007/s40121-020-00338-x</idno>
<idno type="wicri:Area/Main/Corpus">000110</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000110</idno>
<idno type="wicri:Area/Main/Curation">000110</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000110</idno>
<idno type="wicri:Area/Main/Exploration">000110</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.</title>
<author><name sortKey="Waterer, Grant W" sort="Waterer, Grant W" uniqKey="Waterer G" first="Grant W" last="Waterer">Grant W. Waterer</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Western Australia, Perth, Australia. grant.waterer@uwa.edu.au.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Western Australia, Perth</wicri:regionArea>
<wicri:noRegion>Perth</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:affiliation>Northwestern University, Chicago, IL, USA. grant.waterer@uwa.edu.au.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Northwestern University, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rello, Jordi" sort="Rello, Jordi" uniqKey="Rello J" first="Jordi" last="Rello">Jordi Rello</name>
<affiliation wicri:level="3"><nlm:affiliation>Centro de Investigación Biomedica en Red (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Investigación Biomedica en Red (CIBERES), Instituto de Salud Carlos III, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Vall d'Hebron Institute of Research (VHIR), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Clinical Research, CHU Nîmes, Université Montpellier-Nîmes, Nîmes, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Research, CHU Nîmes, Université Montpellier-Nîmes, Nîmes</wicri:regionArea>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Languedoc-Roussillon</region>
<settlement type="city">Nîmes</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Infectious diseases and therapy</title>
<idno type="ISSN">2193-8229</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">COVID-19 is a new infectious disease causing severe respiratory failure and death for which optimal treatment is currently unclear. Many therapies have been proven to be ineffective; however, promising findings related to corticosteroid therapy have been published. Analysis of published data including in this issue suggests that therapy with corticosteroids in the range of 6 mg of dexamethasone (or equivalent) per day likely has a positive effect in patients requiring mechanical ventilation but there remains considerable doubt in patients over the age of 70, in patients with diabetes and patients with milder disease. Clinicians must consider the individual potential risks and benefits of corticosteroid in patients with COVID-19 rather than routinely using them until more data is available.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32936438</PMID>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>16</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">2193-8229</ISSN>
<JournalIssue CitedMedium="Print"><PubDate><Year>2020</Year>
<Month>Sep</Month>
<Day>16</Day>
</PubDate>
</JournalIssue>
<Title>Infectious diseases and therapy</Title>
<ISOAbbreviation>Infect Dis Ther</ISOAbbreviation>
</Journal>
<ArticleTitle>Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All.</ArticleTitle>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s40121-020-00338-x</ELocationID>
<Abstract><AbstractText>COVID-19 is a new infectious disease causing severe respiratory failure and death for which optimal treatment is currently unclear. Many therapies have been proven to be ineffective; however, promising findings related to corticosteroid therapy have been published. Analysis of published data including in this issue suggests that therapy with corticosteroids in the range of 6 mg of dexamethasone (or equivalent) per day likely has a positive effect in patients requiring mechanical ventilation but there remains considerable doubt in patients over the age of 70, in patients with diabetes and patients with milder disease. Clinicians must consider the individual potential risks and benefits of corticosteroid in patients with COVID-19 rather than routinely using them until more data is available.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Waterer</LastName>
<ForeName>Grant W</ForeName>
<Initials>GW</Initials>
<AffiliationInfo><Affiliation>University of Western Australia, Perth, Australia. grant.waterer@uwa.edu.au.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Northwestern University, Chicago, IL, USA. grant.waterer@uwa.edu.au.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rello</LastName>
<ForeName>Jordi</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Centro de Investigación Biomedica en Red (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Vall d'Hebron Institute of Research (VHIR), Barcelona, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Clinical Research, CHU Nîmes, Université Montpellier-Nîmes, Nîmes, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016422">Letter</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>09</Month>
<Day>16</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>New Zealand</Country>
<MedlineTA>Infect Dis Ther</MedlineTA>
<NlmUniqueID>101634499</NlmUniqueID>
<ISSNLinking>2193-6382</ISSNLinking>
</MedlineJournalInfo>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">ARDS</Keyword>
<Keyword MajorTopicYN="N">Coronavirus</Keyword>
<Keyword MajorTopicYN="N">Covid-19</Keyword>
<Keyword MajorTopicYN="N">Pneumonia</Keyword>
<Keyword MajorTopicYN="N">Precision medicine</Keyword>
<Keyword MajorTopicYN="N">RCT</Keyword>
<Keyword MajorTopicYN="N">SARS</Keyword>
<Keyword MajorTopicYN="N">Therapy</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>08</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>9</Month>
<Day>16</Day>
<Hour>12</Hour>
<Minute>17</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>9</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>9</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32936438</ArticleId>
<ArticleId IdType="doi">10.1007/s40121-020-00338-x</ArticleId>
<ArticleId IdType="pii">10.1007/s40121-020-00338-x</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Australie</li>
<li>Espagne</li>
<li>France</li>
<li>États-Unis</li>
</country>
<region><li>Catalogne</li>
<li>Communauté de Madrid</li>
<li>Illinois</li>
<li>Languedoc-Roussillon</li>
<li>Occitanie (région administrative)</li>
</region>
<settlement><li>Barcelone</li>
<li>Madrid</li>
<li>Nîmes</li>
</settlement>
</list>
<tree><country name="Australie"><noRegion><name sortKey="Waterer, Grant W" sort="Waterer, Grant W" uniqKey="Waterer G" first="Grant W" last="Waterer">Grant W. Waterer</name>
</noRegion>
</country>
<country name="États-Unis"><region name="Illinois"><name sortKey="Waterer, Grant W" sort="Waterer, Grant W" uniqKey="Waterer G" first="Grant W" last="Waterer">Grant W. Waterer</name>
</region>
</country>
<country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Rello, Jordi" sort="Rello, Jordi" uniqKey="Rello J" first="Jordi" last="Rello">Jordi Rello</name>
</region>
<name sortKey="Rello, Jordi" sort="Rello, Jordi" uniqKey="Rello J" first="Jordi" last="Rello">Jordi Rello</name>
</country>
<country name="France"><region name="Occitanie (région administrative)"><name sortKey="Rello, Jordi" sort="Rello, Jordi" uniqKey="Rello J" first="Jordi" last="Rello">Jordi Rello</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000577 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000577 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= CovidFranceV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:32936438 |texte= Steroids and COVID-19: We Need a Precision Approach, Not One Size Fits All. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32936438" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a CovidFranceV1
This area was generated with Dilib version V0.6.37. |